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More HLA, More than HLA

The next-generation in genetic matching.

  • Expandable gene content without affecting lab workflow
  • Easy single tube workflow with early indexing step
  • No long-range PCR = no amplification inefficiencies
  • Fast software analysis with data upload at 1 min/sample

The cutting edge solution to detect donor-derived cell-free DNA

AlloSeq cfDNA is a kit based solution that enables measurement of dd-cfDNA through a blood test.

  • A minimally invasive blood test that measures dd-cfDNA
  • A kit based test to run in your own lab and does not require prior genotyping
  • A simple workflow that provides sample to report solution within 24 hours

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  • AlloSeq Tx 17
  • QTYPE
  • TruSight HLA

MORE HLA, MORE THAN HLA

THE NEXT-GENERATION IN GENETIC MATCHING.

AlloSeq Tx 17 offers a single tube workflow and no long-range PCR inefficiencies.

What is AlloSeq Tx17?

AlloSeq Tx 17 helps you to identify the best genetic match by using innovative hybrid capture NGS technology. 

AlloSeq Tx 17 moves beyond the traditional transplant related loci to consider more transplant associated genes.  As we continue to improve our understanding of the “Transplantome™”, additional targets can be added to the AlloSeq Tx 17 assay without impacting workflows or laboratory procedures.

GENE RESOLUTION COVERAGE
HLA-A 4th field Full Gene
HLA-B 4th field Full Gene
HLA-C 4th field Full Gene
HLA-E 4th field Full Gene
HLA-F 4th field Full Gene
HLA-G 4th field Full Gene
HLA-H 4th field Full Gene
DRB1 3rd field Full Exon
DRB3/4/5 3rd field Full Exon
DQA1 3rd field Full Exon
DQB1 3rd field Full Exon
DPA1 3rd field Full Exon
DPB1 3rd field Full Exon
MICA 2nd field Full Exon
MICB 2nd field Full Exon

AlloSeq Tx offers a single tube workflow

Step 1 - Whole Genome Library Generation
Step 2 - Hybrid Capture
Step 3 - Sequencing
Step 4 - Software Analysis

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QTYPE - HLA Typing in Real Time

QTYPE® enables speed and precision in HLA typing at a low to intermediate resolution for samples that require a fast turn-around-time. The QTYPE real time system consists of the QTYPE HLA typing kit and the SCORE 6 interpretation software.

  • Rapid and accurate HLA typing
  • Straightforward analysis
  • Primer/probe technology increases capacity for future expansion

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TruSight HLA

TruSight® HLA v2 Sequencing Panel provides clinical researchers with a broad-coverage, high–resolution human leukocyte antigen (HLA) typing solution for simple, rapid assessment of the HLA region in a single assay.

Interested in the next-generation in genetic matching that offers a single tube workflow and no long-range PCR inefficiencies?

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  • AlloSeq cfDNA

The cutting edge solution to detect donor-derived cell-free DNA

AlloSeq cfDNA is a kit based solution that enables measurement of dd-cfDNA through a blood test

What is AlloSeq cfDNA?

  • A minimally invasive blood test that measures dd-cfDNA
  • A kit based test to run in your own lab and does not require prior genotyping
  • A simple workflow that provides sample to report solution within 24 hours

WHAT IS CELL-FREE DNA (CFDNA)?

  • Cell-free DNA refers to fragments of DNA in the bloodstream that originate from cells undergoing cell injury and death
  • DNA degrades into nucleosomal units consisting of ~166 bases
  • Cell-free DNA is cleared from the blood by the liver and kidney and has a half-life of about 30 minutes

ALLOSEQ CFDNA = ALLOSURE, AND IT IS VALIDATED

  • AlloSure dd-cfdna is validated in a 14 center prospective study
  • Broadly used in over 150 transplant centers
  • Used in re-transplants

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Additional CareDX Lab Products

Find out about our Olerup SSP®, Olerup SBT™, and Olerup XM-ONE® products .

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